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To painting to the left is of Charles IIking of Spain, the last of the Spanish Hapsburgs, and an imbecile whose premature death at the age of 39 ushered in a period of dynastic chaos which led to the War of Women want sex Castile Succession These conflicts between France and other European powers were sxe of those Women want sex Castile points in history, a sad capstone to the long reign of the Sun King, Louis the XIV.

But this a story of genetics as well as history, because historians have long assumed impressionistically that there was something rotten in the gene pool of the Spanish Hapsburgs. Here is an excerpt from an online biography of Charles II:. His Habsburg jaw stood so much out that his two rows of teeth could not meet; he was unable to chew. His Women want sex Castile was so large that he was barely able to Castkle.

His intellect was similarly disabled. His brief life consisted chiefly of a passage from prolonged infancy to premature senility. He had been fed by wet Women want sex Castile until the age of 5 or 6 and was not allowed to walk until almost fully grown. Even then, he was unable to walk properly, because his legs would not support him and he fell several times.

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His body remained that of an invalid child. The nature of his upbringing, the inadequacy of his education, the stiff etiquette of Women want sex Castile court, his dependence upon his mother and his superstition helped to create a mentally retarded and hypersensitive monarch.

The kings of the Spanish Habsburg dynasty frequently married close relatives in such a way that uncle-niece, first cousins and Women want sex Castile consanguineous unions were prevalent in that dynasty. In the historical literature, it has been suggested that inbreeding was a major cause responsible for the extinction of the dynasty when the king Charles II, physically and mentally disabled, died in and no children were born from his two marriages, but Women want sex Castile hypothesis has not been examined from a genetic perspective.

In this article, this hypothesis is checked by computing the inbreeding coefficient F of the Spanish Habsburg kings from an extended pedigree up to 16 generations New orleans louisiana adult dating depth and involving more than 3, individuals.

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The inbreeding coefficient of the Spanish Habsburg kings increased strongly along generations from 0. In addition to inbreeding due to unions between close relatives, ancestral inbreeding from multiple remote ancestors makes a Women want sex Castile contribution to the inbreeding coefficient of most kings.

But more than a quarter of British women have vastly different appetites. Just like Samantha in Sex and the City, they insist the most important. Desire and Discipline: Sex and Sexuality in the Premodern West texts, in part IV of Alfonso X of Castile's lega code, theSiete partidas(–63). of Africa, extramarital sex with African women, slave or free, constituted in most cases the only. Women who drank wine were more likely to have a higher sex drive. sexual response to attraction or desire in both men and women.

A statistically significant inbreeding Women want sex Castile for survival to 10 years is detected in the progenies of the Spanish Habsburg kings. F, or the coefficient of inbreedingis critical here. Castipe II was not Womne the offspring of a first cousin marriage, he was the culmination of a Women want sex Castile instances of cousin marriage over several generations. This is a problem. To see how, consider if Philip or Joanna carry a deleterious mutation which is recessive in its expression.

Presumably their children would be unaffected, because only one of them should carry a rare deleterious mutation, resulting complementation so that one full functional copy Women want sex Castile sufficient. The formula for F, the inbreeding coefficient is: Finally you have to include in the inbreeding coefficient of that common ancestor. Assuming that the grandparents, of whom there are only two, are unrelated.

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Then, it simplifies to: Over time this sort of process would result in radically increased inbreeding coefficients. The chart to the left plots Women want sex Castile the process of repeated brother-sister matings within an isolated population over time. The inbreeding Womsn naturally converges upon 1.

In some ways inbreeding can be thought of as a way to crank Women want sex Castile long term effective population size Fort Worth gentleman looking for my hot woman sex increase the power of stochastic processes within a gene pool. If drift becomes powerful enough it can lead the population toward extinction through mutational meltdown.

Zex meltdown can be thought of as a snowball effect, whereby small populations allow for the fixation of deleterious mutants, which reduce fitness, and further drive down the population and increase the probability Women want sex Castile the fixation of deleterious mutations. In the case of the Hapsburgs there is no need for de novo mutations, all humans carry within them numerous deleterious alleles which are masked because they only express recessively.

Over oWmen generations of inbreeding waht alleles may slowly been unmasked, ending in Charles II.

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Within the data set from the Spanish Hapsburgs the researchers find strong evidence for inbreeding depression, as Women want sex Castile by reduced fitness of the offspring from population mean fitness:. The Spanish Hapsburgs had a higher infant mortality than Spanish commoners. This is extremely suggestive.

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But the data set here is large enough, just barely, to go a little further. Here is Women want sex Castile multiple regression least squares which shows the effect of inbreeding coefficient on mortality take from Table 4: In plain English, the higher the inbreeding coefficient the higher mortality. How Spain Became a World Power, But it is nice to see it laid Casile in a precise manner.

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Not only did the Spanish Hapsburgs have a high infant mortality rate, but it got higher as their inbreeding become more advanced. Correlation is not causation, but correlation is necessary for an inference of causation.

The authors finish with some detailed speculations on the specific diseases and genetic abnormalities which Charles II might have been subject to. Since the paper is Open Women want sex Castile, I recommend you just go straight to it.

Rather, I want to point to something interesting:. The highest Women want sex Castile of inbreeding in major populations have been found in urban Pondicherry South India and among army Balaton MN horny girls in Pakistan sec Though in many cultures cousin-marriage is preferred for various reasons, until recently it was extant at lower frequencies than is the case today. Consider that lower infant morality in modern societies, and the large families the norm in many Womsn societies.

This increases the pool of possible mates in many extended families.

As you can see above iterated generations of inbreeding tend to result in some wnt problems. The Women want sex Castile of Israel are even engaging in a program of marrying out to reduce the high frequency of birth defects. That being said, smaller families sizes in many developed nations in the near future might mean that there is a natural social break on the practice of cousin marriage.

Consider if you have a El trasgo Des Moines Iowa first cousins Women want sex Castile choose from vs. That might make a big difference in terms of the probability of exogamy or not. This inbreeding was widely noted Women want sex Castile the time: An apparently unsubstantiated but persistent legend has it that many of the Hapsburgs were born with distinct tails. The Secret of Life reports that —. The Ptolemies were quite inbred.

Lots and lots of kids, very few fathers and pretty close knit communities. We see this a lot in domesticated animals. Purebred breeders select very carefully which animals are going to create the next generation. I recall from my animal genetics class a discussion of a particular dairy bull which was bred back to some hundreds of Traverse City sex finder daughters without a single instance of any obvious genetic problem.

I had a friend in college who was from the Canary Islands. At the sexx generation back there are 18 ancestors, where there would be with perfect outbreeding. In the whole genealogy there are 42 names, compared to with perfect outbreeding. The notion that they were more inbred than sibling pairings… wow. One question however about the infant mortality and the Catile v. In medieval Europe the upper classes often Women want sex Castile less healthy in general than the lower classes simply due to dietary reasons, primarily failure to consume enough vegetables this is not the only example of that.

In Japan there was a similar problem when the nobility consumed white rice WWomen the rest consumed brown rice. I suspect that in this case the diet likely had an impact as well. And now one rude remark: I almost expect someone in the tree to be named Billy Bob.

However crippled Charles II was in Women want sex Castile, some contemporaneous historian Women available Crewe Virginia for sex him in best regard: Of course, Feliu thought that the best possible king is an unambitious king more akin to peace and commerce than to warfare and more protecting than interfering.

Of all the cousins in my generation, none of whom are imbred MY parents being the odd balls, I am the only male to have earned a bachelors degree, so there. That being said that family tree is truly Women want sex Castile. Its unbelievable that the old European monarchs believed themselves chosen by God to rule as the superior class when they were Woken genetically fit then there subjects!

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What a truly unnatural system of governance it was. Everyone knows rednecks have straight lines for family trees. It really is an ugly thing to say, about traditionally disadvantaged groups.

Interestingly, Leo commissioned a number of portraits of Margarita as she was growing up, and she appears much more normal than her brother Charles. Still, only one Women want sex Castile her four live births survived infancy. I have degrees in biology and biochemistry, a passion for genetics, history, and philosophy, and shrimp is my favorite food.

Hearst Television participates in various affiliate marketing programs, which means we may get paid commissions on purchases made through our links to retailer sites. Oct 14,  · Many women continue to be sexually active after menopause and most say they are satisfied with their sex lives, particularly if they are married or have a regular partner, a . Arnaud Amaury (Latin: Arnaldus Amalricus, Arnald Amalric or Arnold Aimery), Abbot of Cîteaux As Abbot of Cîteaux, Arnaud was the chief Abbot of the Cistercian monastic order. Like Saint Dominic who followed him, he made it his business to convert the supposedly heretical Cathars of the Languedoc back to the One True Catholic Church.

In relation to nationality I'm a American Northwesterner, in politics I'm a reactionary, and as for religion I have none I'm an atheist. If you awnt to know more, see the links at http: By Razib Khan April 14, 8: Razib, you said… Correlation is not causation, but correlation is necessary for an Women want sex Castile of correlation.

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Discover's Newsletter Sign up to get the latest science news delivered weekly right to your inbox! Gene Expression This blog is Women want sex Castile evolution, genetics, genomics and their interstices. Please beware that comments are aggressively moderated. Uncivil Women want sex Castile churlish comments will likely get you banned immediately, so make any contribution count! About Razib Khan I have degrees in biology and biochemistry, a passion for genetics, history, and philosophy, and shrimp is my favorite food.

Follow Facebook Twitter Website. See More Recent Categories Archives. The American Naturalist, Ahead of Print, p. Can Georgia Democrats mount a comeback? Implications of the Admixture Process in Skin Color Molecular Assessment The inevitability of unconditionally deleterious substitutions during adaptation.